A RELIABLE TEST FOR GASTROINTESTINAL LESIONS

粪便潜血试验（FOBT）通常用于检测血液释放 胃肠道病变 例如，结肠直肠癌是最常见的严重 癌症在美国（每年新增10万例，死亡5万例）。 因为 其进展相对缓慢，无症状期较长， 结肠直肠癌为早期发现提供了理想的机会， 成功的治疗 因为结肠直肠癌和不稳定的病变 经常出血，FOBT是早期发现的合理尝试。 同样，医院和医生经常使用FOBT来检测和 监测由疾病、损伤、手术等引起的胃肠道病变。 许多临床研究表明，目前的FOBT患有严重的 灵敏度和特异性的局限性。 不幸的是， 替代品不再是简单，快速，成本效益，现场临床 工具. 该项目将展示更新当前FOBT技术的可行性 提高临床性能，同时保留关键用户优势。

Fecal Occult Blood Tests (FOBT) are commonly used to detect blood released from GI lesions. For example, colorectal cancer is the most common serious cancer in the U.S. (100,000 new cases and 50,000 deaths annually). Because it is relatively slowly progressive with a long asymptomatic period, colorectal cancer provides an ideal opportunity for early detection and successful therapy. Since colorectal cancers and precarious lesions frequently bleed, FOBT are a rational attempt at early detection. Similarly, hospitals and physicians frequently utilize FOBT to detect and monitor GI lesions resulting from disease, injury, surgery, etc. Numerous clinical studies illustrate that current FOBT suffer from serious limitations in sensitivity and specificity. Unfortunately, proposed alternatives are no longer simple, rapid, cost effective, on-site clinical tools. This project will show the feasibility of updating current FOBT technology to improve clinical performance while retaining key user advantages.