TARGeTED: Tackling Antimicrobial Resistance through Goal-orientated Thinking in the EPS Disciplines
TARGeTED: Tackling Antimicrobial Resistance through Goal-orientated Thinking in the EPS Disciplines
批准号:
EP/M027538/1
负责人:
Margaret Smith
金额:
$51.34万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2015
资助国家:
英国
项目状态:
已结题
起止时间:
2015 至 --
中文摘要
抗微生物药物耐药性(AMR)是对人类和动物健康的严重威胁。这个问题是多因素的,跨越许多学科,涉及整个社会的利益相关者。我们的信念是,通过与不同学科的研究人员合作,我们可以提出新的问题,并开发新的解决方案,以应对抗生素耐药性的挑战。从事EPS的科学家可以为抗菌素耐药性挑战的许多方面带来新颖的见解和创新的技术,但他们参与以目标为导向的跨学科研究存在障碍。我们已经确定了导致成功的跨学科研究成果的条件;接受,理解,沟通,资源和网络。我们已经制定了一个活动计划,将为来自EPS的研究人员创造时间和空间,让他们以一种能够确定他们可以解决的可处理问题的方式来参与思考抗菌素耐药性挑战。首先,我们将专注于约克大学目前正在进行的卓越研究领域,这些领域迄今尚未应用于抗生素耐药性研究,但有望提供新的见解和创新的解决方案。这些领域是“理解和控制细菌行为的新工具”和“新型生物传感器和诊断”。我们认识到,一个成功的“弥合差距”项目将把尚未参与抗微生物药物耐药性议程的研究人员之间的合作结合起来,我们已经将接触这些人的活动战略纳入我们的活动战略。结果将是一个令人兴奋的跨学科研究人员社区,他们致力于AMR的挑战,他们正在交流,激发想法,撰写论文并申请进一步的资助。
英文摘要
Antimicrobial resistance (AMR) is a serious threat to human and animal health. The problem is multifactorial, spans across many disciplines and involves stakeholders from right across society's spectrum. Our belief is that by engaging researchers from different disciplines, we can ask new questions and develop new solutions to the AMR challenge. Scientists engaged in EPS can bring novel insights and innovative technologies to many aspects of the AMR challenge but there are barriers to their engagement with goal-orientated, inter-disciplinary research. We have identified the conditions that lead to successful inter-disciplinary research outcomes; receptiveness, understanding, communication, resources and networks. We have put together a programme of activities that will create the time and space for researchers from EPS to engage in thinking about the AMR challenge in such a way that they will be able to identify tractable problems that they can solve. To start with we will focus on areas of research excellence currently being conducted at the University of York that have not to date been applied to AMR research, but promise to provide new insights and innovative solutions. These areas are 'Novel tools for understanding and controlling bacterial behaviour' and 'Novel biosensors and diagnostics'. We recognize that a successful 'Bridging the Gap' programme will bring together collaborations between researchers not yet engaged with the AMR agenda and we have incorporated into our activities strategies to reach these people. The outcome will be an exciting community of inter-disciplinary researchers working on the challenges of AMR that are communicating, sparking ideas, writing papers and applying for further funding.
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DOI:
10.1007/s11538-017-0288-z
发表时间:
2017-06
期刊:
Bulletin of mathematical biology
影响因子:
3.5
作者:
[Alfiniyah C, Bees MA, Wood AJ]
通讯作者:
Wood AJ
DOI:
10.3389/fmicb.2018.00195
发表时间:
2018
期刊:
Frontiers in microbiology
影响因子:
5.2
作者:
[Flanagan L, Steen RR, Saxby K, Klatter M, Aucott BJ, Winstanley C, Fairlamb IJS, Lynam JM, Parkin A, Friman VP]
通讯作者:
Friman VP
Bugs on a Slippery Plane : Understanding the Motility of Microbial Pathogens with Mathematical Modelling.
滑平面上的虫子:通过数学模型了解微生物病原体的运动性。
DOI:
10.1007/978-3-319-32189-9_12
发表时间:
2016
期刊:
Advances in experimental medicine and biology
影响因子:
--
作者:
[Pushkin DO]
通讯作者:
Pushkin DO
Fast antimicrobial susceptibility test based on hydrodynamic trapping of single bacteria
基于单一细菌水动力捕获的快速抗菌药敏试验
DOI:
--
发表时间:
2018
期刊:
22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
影响因子:
--
作者:
[Pitruzzello G.]
通讯作者:
Pitruzzello G.
DOI:
10.1038/srep35646
发表时间:
2016-10-19
期刊:
Scientific reports
影响因子:
4.6
作者:
[Privat-Maldonado A, O'Connell D, Welch E, Vann R, van der Woude MW]
通讯作者:
van der Woude MW
SBIR Phase I: A language learning app based on sound and mouth movements
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批准号:2323040
-
项目类别:Standard Grant
-
资助金额:$27.47万
-
财政年份:2023
-
负责人:Margaret Smith
-
依托单位:
Novel industrial bioprocesses for production of key valuable steroid precursors from phytosterols
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批准号:BB/L003619/1
-
项目类别:Research Grant
-
资助金额:$39.79万
-
财政年份:2013
-
负责人:Margaret Smith
-
依托单位:
Overcoming antibiotic resistance by studying antibiotic hypersensitivity
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批准号:BB/J016691/1
-
项目类别:Research Grant
-
资助金额:$69.6万
-
财政年份:2012
-
负责人:Margaret Smith
-
依托单位:
New recombinases for genome engineering
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批准号:BB/H005447/1
-
项目类别:Research Grant
-
资助金额:$41.75万
-
财政年份:2010
-
负责人:Margaret Smith
-
依托单位:
The mechanism of phiC31 integrase; a unidirectional recombinase for genome engineering
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批准号:BB/H001212/1
-
项目类别:Research Grant
-
资助金额:$52.63万
-
财政年份:2009
-
负责人:Margaret Smith
-
依托单位:
A systems approach to understanding metabolic switching in Streptomyces coelicolor
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批准号:BB/F003439/1
-
项目类别:Research Grant
-
资助金额:$41.27万
-
财政年份:2007
-
负责人:Margaret Smith
-
依托单位:
Cases of Reasoning and Proving in Secondary Mathematics (CORP)
-
批准号:0732798
-
项目类别:Continuing Grant
-
资助金额:$210.13万
-
财政年份:2007
-
负责人:Margaret Smith
-
依托单位:
The mechanism of phiC31 integrase; a tool for gene therapy and genome manipulation
-
批准号:BB/D007836/1
-
项目类别:Research Grant
-
资助金额:$58.67万
-
财政年份:2006
-
负责人:Margaret Smith
-
依托单位:
ESP: Enhancing Secondary Mathematics Teacher Preparation
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批准号:0301962
-
项目类别:Continuing Grant
-
资助金额:$0.0万
-
财政年份:2003
-
负责人:Margaret Smith
-
依托单位:
Applied Research -- A Study of Teacher Education: Research on Instructional Design (Project ASTEROID)
-
批准号:0101799
-
项目类别:Continuing Grant
-
资助金额:$60.88万
-
财政年份:2001
-
负责人:Margaret Smith
-
依托单位:
COMET: Cases of Mathematics Instruction to Enhance Teaching
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批准号:9731428
-
项目类别:Continuing Grant
-
资助金额:$27.62万
-
财政年份:1998
-
负责人:Margaret Smith
-
依托单位:
海外基金