FACTORS AFFECTING DISTRIBUTION OF MYOCARDIAL FLOW

拟议的研究将继续阐明多种因素， 控制心肌灌注。 与过去一样，这项工作的目的是 回答生理学和病理生理学定义中的重要问题 冠状动脉血流量的动物模型，这是非常类似的人在一个 生理状态 因此，这项工作将在清醒的动物身上进行 模型 研究建议包含两个具体目标：1）逐搏 调节冠状动脉血流，和2）物理，药理学和 影响心房血流的神经因素。

The proposed research will continue to elucidate the multiple factors which control myocardial perfusion. As in the past, the aim of this work is to answer questions important in defining the physiology and pathophysiology of coronary blood flow in animal models which are closely akin to man in a physiologic state. Thus, this work will be carried out in awake animal models. The research proposal contains two specific aims: 1) beat-to-beat regulation of coronary blood flow, and 2) physical, pharmacologic and neural factors which affect atrial blood flow.