I-Corps: Wearable Magnetoelastic Generator for Atrial Fibrillation

I-Corps：用于心房颤动的可穿戴磁弹发生器

• 批准号: 2324601
• 负责人: Jun Chen
• 金额: $ 5万
• 依托单位: University of California-Los Angeles
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2324601&HistoricalAwards=false
• 关键词: Corps; Wearable; Magnetoelastic; Generator; Atrial

The broader impact/commercial potential of this I-Corps project is the development of a magnetoelastic generator (MEG) bracelet for cardiac monitoring. Current devices need an external power supply and intermittent charging and provide monitoring for up to two months. Implantable devices can do so for two years. In contrast, the proposed bracelet employs a self-powered two-step energy conversion method that continuously transforms pulses into high-fidelity, analyzable electrical signals without requiring a power source. This allows for uninterrupted monitoring. Currently used devices are not continuous and inconvenient to use because they require the patient to measure their pulse deliberately. The proposed device's continuous data collection feature eliminates the problems of battery drainage and intermittent charging periods. Additionally, this device may be used as a non-invasive and continuous diagnostic tool.This I-Corps project is based on the development of a device to monitor atrial fibrillation. It uses human arterial pulse waves and converts them into high-fidelity and analyzable electrical signals, working in a self-powered manner. The device utilizes the giant magnetoelastic effect in soft systems, making it adaptable for wearable bioelectronics. The proposed textile wearable magnetoelastic generator (MEG) consists of two types of fibers and operates on a two-step energy conversion, including mechanical-to-magnetic and magnetic-to-electrical conversions. A weaving of those fibers will complete the cycle of mechanical-to-electrical conversion. This makes the device self-powered and eliminates the need for an external power source such as a battery. In addition, since magnetic fields can pass through water without significant performance loss, the device is intrinsically waterproof. Previous research testing the efficiency of the materials and reliability of the MEG in-vitro compared favorably with traditional blood pressure monitors with a 1.2% difference. In addition, the proposed technology may be implemented to measure heart rate, respiratory rate, and movements, leading to the development of more accurate, efficient, and non-invasive diagnostic tools.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

I-Corps项目的更广泛影响/商业潜力是开发用于心脏监测的磁弹性发电机手镯。目前的设备需要外部电源和间歇充电，并提供长达两个月的监测。 可植入设备可以这样做两年。 相比之下，所提出的手镯采用自供电的两步能量转换方法，该方法连续地将脉冲转换成高保真的、可分析的电信号，而不需要电源。这样就可以进行不间断的监控。 目前使用的设备是不连续的，并且使用不方便，因为它们需要患者故意测量他们的脉搏。 所提出的设备的连续数据收集功能消除了电池放电和间歇充电周期的问题。此外，该设备可用作非侵入性和连续的诊断工具。该I-Corps项目是基于开发一种监测房颤的设备。它使用人体动脉脉搏波，并将其转换为高保真和可分析的电信号，以自供电的方式工作。该设备利用软系统中的巨磁弹性效应，使其适用于可穿戴生物电子学。所提出的纺织可穿戴磁致弹性发电机（MEG）由两种类型的纤维组成，并进行两步能量转换，包括机械到磁性和磁性到电气转换。这些纤维的编织将完成机械到电气转换的循环。这使得设备自供电，并消除了对电池等外部电源的需要。此外，由于磁场可以穿过水而没有显著的性能损失，因此该设备本质上是防水的。先前的研究测试了材料的效率和体外MEG的可靠性，与传统的血压监测仪相比，差异为1.2%。此外，拟议的技术可以实现测量心率，呼吸率和运动，导致更准确，有效，和非侵入性的诊断工具的发展。这个奖项反映了NSF的法定使命，并已被认为是值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估的支持。