ULTRASONICALLY ACTIVATED SCALPEL FOR BLOODLESS SURGERY

皮肤科医生和整形外科医生需要 产生控制良好的无血切口 而普通的冷钢 解剖刀使外科医生能够控制切割的长度和深度 （取决于个人技能），手术野并非没有血。 为 在许多应用中，自烧灼刀片显然是有利的。 手术器械，如激光、电化学烧灼器、加热手术刀 并且目前正在使用超声波探头。 与以下方面相关的缺点 这些装置的使用包括组织损伤、结疤和增加的风险 感染 最近，已经引入了超声波吸引器。 虽然这种吸引器被证明对某些肝脏切除有效， 在手术中，它不能有效地切割柔韧的组织， 胃壁 能源和矿产研究公司已经推出了一个 用于工业用途的超声刀，称为ULTRAKNIFEtm。 该刀具可使用明显较低的力切割各种材料。 其他超声激活的外科器械诱导轻度止血， 对周围组织的损伤很小。 我们相信我们的改良版 手术刀是一种上级手术刀， 手术 一个研究原型超声激活手术刀将 根据研究计划的结果进行组装，并交付给 宾夕法尼亚大学医院皮肤科小组， 评价 他们的评价将构成最后报告的一部分， 一阶段 如果评估是积极的，第二阶段的计划，以制定一个 将提出超声刀。 虽然没有市场研究， 确定这种工具的市场价值，我们预计， 整个医疗行业的需求将非常广泛。

There exists a demand on the part of dermatologists and plastic surgeons to produce well controlled, bloodless incisions. While the common, cold-steel scalpel provides surgeons with control over length and depth of cut (dependent on individual skills), the surgical field is not bloodless. For many applications, a self-cauterizing blade would be clearly advantageous. Surgical devices such as lasers, electrochemical cauteries, heated scalpels and ultrasonic probes are currently in use. Disadvantages associated with the use of these devices include tissue damage, scarring and increased risk of infection. Recently, an ultrasonic aspirator has been introduced. While this aspirator proved effective for certain liver resection procedures, it is not effective in cutting through pliable tissue such as stomach walls. Energy and Minerals Research Company has introduced an ultrasonically activated knife for industrial use called the ULTRAKNIFEtm. This tool cuts a wide variety of materials using markedly lower force. Other ultrasonically activated surgical devices induce mild hemostasis with little damage to surrounding tissues. We believe a modified version of our knife will be a superior scalpel that will also induce hemostasis during surgery. A research prototype ultrasonically activated scalpel will be assembled based on the findings of the research program and delivered to the Dermatology Group of the University of Pennsylvania Hospital for evaluation. Their evaluation will comprise part of the Final Report for Phase I. If the evaluation is positive, a Phase II program to develop a ultrasonic scalpel will be proposed. Though no market studies exist to determine the dollar value of a market for such a tool, we expect that demand will be widespread throughout the medical industry.