空心粘膜假体的体外上皮化-猫眼课题宝

空心粘膜假体的体外上皮化

批准号：

3495717

负责人：

RICHARD E HOFFER

金额：

$5.0万

依托单位：

DESERET RESEARCH COMPANY

依托单位国家：

美国

项目类别：

财政年份：

1988

资助国家：

美国

项目状态：

已结题

起止时间：

1988-09-15 至 1989-06-14

来源：

https://reporter.nih.gov/project-details/3495717

关键词：

autologous transplantation biomaterial development /preparation biomaterial evaluation cell growth regulation collagen cow dogs histology polyethylenes regeneration tissue /cell culture tissue support frame urinary bladder epithelium urinary tract prosthesis urinary tract surgery wound healing

中文摘要

翻译

这项拟议的研究旨在开发和评估一种方法体外上皮化，一种复合的中空内脏假体由外部硬质多孔材料和可生物降解的内层。膀胱壁假体的愈合将在狗身上进行评估。假体将接受尿液检查。渗漏、感染、挤压、排斥，合并到膀胱壁，膀胱造影示结石形成；肉眼和光学显微镜。

英文摘要

This proposed study is designed to develop and evaluate a method of epithelizing, in vitro, a compound hollow viscus prosthesis consisting of an outer rigid porus material and a biodegradable inner layer. Healing of the prosthesis in the wall of the urinary bladder will be evaluated in dogs. The prosthesis will be evaluated for urine leakage, infection, extrusion, rejection, incorporated into the urinary bladder wall, and calculus formation by cystography, and gross and light microscope.

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