NON-SURFACTANT FORMULATION FOR INDUCING AGENTS

据报道，服用以下药物后会出现不良反应 溶解于水中的化合物。这种副作用可能是 通过结合主要诱导剂阿法索酮来减少或消除， 用环糊精，它已经被证明可以改善溶解性和 其他类固醇的疗效。对大鼠模型的初步研究表明 对这种组合的承诺。这项技术的成功开发 将为非表面活性剂配方提供一种安全的替代品 诱导剂，减少毒副作用，让安全可靠 麻醉。

Adverse reactions have been reported to occur after administration of compounds solubilized in aqueous vehicles. This side-effects may be reduced or eliminated by combining the primary inducing agent, alfaxalone, with cyclodextrins, which have been shown to improve solubility and efficacy of other steroids. Preliminary studies in a rat model show promise for this combination. Successful development of this techniques will provide a safe alternative for a non-surfactant formulation for the inducing-agent, reducing toxic side-effects and allowing safe and reliable anesthesia.