NEUROMUSCULAR BLOCKADE MONITOR USING MOTION SENSOR

有必要更好地监测和控制神经肌肉阻滞，以 测量患者在手术过程中是否充分瘫痪，并 促进重症监护病房(ICU)的机械通风。在……里面 第一阶段，我们开发了一种用于手术室的神经肌肉监测器。它 监护仪提供电刺激并测量患者的运动 用压电薄膜传感器。监视器和一次性传感器在 12例患者。它被发现与其他监测技术一样准确。 在第二阶段，我们将为ICU开发一种神经肌肉阻滞监护仪。 临床研究将证明脚踝和脚是合适的。 监测部位和次极量电刺激提供 足够的信号强度，但对患者来说痛苦较小。在第二阶段 我们还将开发一种药物输液泵的闭环控制器。 控制器将自动保持所需的瘫痪程度。 这项工作将以单板的开发和测试结束 显示器和控制器的计算机版本，以OEM方式销售 给注射器泵制造商。

There is a need to better monitor and control neuromuscular blockade, to measure whether a patient is adequately paralyzed during surgery and to facilitate mechanical ventilation in the Intensive Care Unit (ICU). In Phase I, we developed a neuromuscular monitor for the operating room. It monitor delivers an electrical stimulus and measures the patient's movement with a piezo film sensor. The monitor and disposable sensor were tested in 12 patients. It is found to be as accurate as other monitoring techniques. In Phase II, we will develop a neuromuscular blockade monitor for the ICU. Clinical studies will demonstrate that the ankle and foot are appropriate monitoring sites and that submaximal electrical stimulation provides adequate signal strength, but is less painful to the patient. In Phase II we will also develop a closed-loop controller for a drug infusion pump. The controller will automatically maintain the desired level of paralysis. This work will conclude with the development and testing of a single board computer version of the monitor and controller, to be sold on an OEM basis to syringe pump manufacturers.