SHARED NMR/X-RAY CRYSTALLOGRAPHY SUPERCOMPUTER FACILITY

生物化学和分子药理学系 哈佛医学院建立了一个全面的结构 生物学课程，自1988年以来招聘了7名新教师 他们是这项提案的核心教员。该计划包括一个 具有四个高场光谱仪的核磁共振基团和X射线结晶学 哈佛医学院四边形上的小组(两台发电机， 探测器等)，以及相邻的X射线结晶组 Dana-Farber癌症研究所(一个发电机、探测器等)。这 提案要求提供资金以购买共享的超级计算机设施，以 支持和加强BCMP结构生物学计划。主要用户 由12名《蒙特利尔议定书》调查员组成的小组，位于四合院和 Dana-Farber已提出并已组装成可访问和利用 超级计算的计算、建模和图形能力 设施。

The Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School has established a comprehensive Structural Biology program, with the recruitment of seven new Faculty since 1988 who serve as core faculty for this proposal. This program includes an NMR group with four high-field spectrometers, and X-ray crystallography group on the Harvard Medical School Quadrangle (two generators, detectors, etc.), and an X-ray crystallography group at the adjacent Dana-Farber Cancer Institute (one generator, detector, etc.). This proposal requests funds to acquire a shared supercomputer facility to support and enhance the BCMP Structural Biology Program. A major user group of 12 BCMP investigators, located on the Quadrangle and at the Dana-Farber is proposed and already assembled to access and utilize the computational, modelling and graphic capabilities of the supercomputing facility.