REQUEST FOR IMB EPR/200D SPECTROMETER

本申请的目的是更换过时的EPR光谱仪， 由于需要更新我们的分析方法和采取 新开发的技术的优势和目前的情况 光谱仪，现在需要以相当高的成本不断维修 浪费了宝贵的研究时间。 UOP的基础科学教员人数不多，但积极参与其中 在众多的研究项目中。研究的主要部分是 肌浆网钙离子转运机制的研究 (Sr)，允许团体和 持续的思想和信息交流。电子自旋共振 证明了这是一个有价值的工具，研究的构象和机制 膜结合SR-ATPase及其结构性质的研究 脂类。主要调查者的研究涉及广泛。 用电子顺磁共振波谱。然而，在某种程度上，每个研究小组 与SR相关的人员以前使用过或当前需要EPR 技巧。

The purpose of this request is to replace an obsolete EPR spectrometer, necessitated by both the need to update our methods of analysis and take advantage of newly developed techniques and by the present condition of the spectrometer which is now in need of constant repair at considerable cost and loss of valuable research time. The basic science faculty at U.O.P. is not large but is actively involved in numerous research projects. The major portion of the research is directed towards the mechanism of Ca++ transport in Sarcoplasmic Reticulum (SR), allowing for frequent collaborative efforts between groups and an ongoing exchange of ideas and information. Electron spin resonance has proven to be a valuable tool in studing the conformation and mechanism of the membrane bound SR ATPase as well as the structural properties of the SR lipids. The research of the principal investigator is extensively involved with EPR spectroscopy. However, to some degree, every research group concerned with SR has either previously used or is in current need of EPR techniques.