MOLECULAR BIOLOGY FACILITY GRANT

本建议书适用于购置下列设备的部分直接费用： 4件仪器，将包括一个分子 生物学/分子遗传学核心设施 微生物学和免疫学研究实验室 罗切斯特大学医学中心。 这些项目已应用 Biosystems蛋白质/肽测序仪、肽合成仪、DNA 测序仪和奥利诺肽合成仪。 一组12个主要 每个用户与小灵通同行审查赠款支持已 鉴定 这所大学里没有这样的设施。 适当 已经确定了技术方面的机构支助， 协助，并购买所有额外的支持设备。 新建的实验室空间已在新的 微生物学研究实验室， 毗邻大学医院和研究人员在 微生物学和免疫学系，内科， 儿科和癌症中心 设施咨询 由亚伯拉罕博士和伊格卢斯基博士领导的委员会， 由L博士。塔巴克博士科恩和J·弗雷林格将 监督设施的使用和运作。 人们希望 这个分子生物学设施将形成一个活动中心， 在上述部门的研究。

This proposal is applying for partial direct costs for acquisition of 4 pieces of instrumentation which will comprise a molecular biology/molecular genetics core facility in Department of Microbiology and Immunology research laboratories at the University of Rochester Medical Center. These items are Applied Biosystems protein/peptide sequenator, Peptide synthesizer, DNA sequencer and olinonucleotide synthesizer. A group of 12 major users each with PHS peer-reviewed grant support has been identified. No such facility exists in this University. Appropriate institutional support has been identified for the technical assistance, and purchase of all additional supporting equipment. Newly constructed laboratory space has been defined in the new department of Microbiology research laboratories which is contiguous to the university hospital and investigators in the departments of Microbiology and Immunology, Internal Medicine, and Pediatrics, and the cancer center. A facility advisory committee headed by Dr. Abraham and Dr. Iglewski and comprised of Dr. L. Tabak, Dr. H. Cohen, and J. Frelinger will monitor the use and functioning of the facility. It is hoped that this molecular biology facility will form and active center for research in the above departments.