Colonic dysmotility is a significant aetiological factor in faecal incontinence

大便失禁是令人尴尬的，可以破坏病人的生活质量。虽然肛门括约肌在控制排便方面起着重要作用，但患者可以具有正常的括约肌功能，并且仍然遭受严重的尿失禁。在这个项目中，我们将使用我们独特的记录技术，以确定在这些患者的远端结肠收缩力的异常区域，并表明这有助于失禁。这些数据将为治疗提供新的靶向区域。

Faecal incontinence is embarrassing and can ruin a patient’s quality of life. While the anal sphincters play an important role in controlling defaecation, patients can have normal sphincter function and still suffer severe incontinence. In this project we will use our unique recording techniques to identify an abnormal region of contractility in the distal colon of these patients and show that this contributes to the incontinence. These data will provide a new targeted region for treatment.