Sustainable Chemicals Innovations Enabling Net Carbon Emissions (SCIENCE)

英国最近朝着清洁增长迈出了大胆的一步，就到2035年结束传统柴油和汽油乘用汽车的销售，并到2050年实现零排放汽车车队进行了咨询。这些雄心确实大胆，但它们给汽车行业及其供应链带来了额外的压力，要求其进行创新，并突出了对现有汽车车队未来环境可行性的担忧。除了必须克服的明显的科学，环境和技术障碍，以实现大规模电气化（假设这是采用的并且是最低的环境影响），这些雄心激发了减少传统内燃机（ICE）在所有规模运输中的影响的意识。迫切需要提高效率，同时减少车辆的综合、终身碳足迹，这促使人们对燃油效率、维护频率以及所有ICE相关消耗品的影响进行审查。到目前为止，路博润的产品在所有内燃机平台上使用的燃油和机油添加剂中占很大比例，这些产品直接促进并帮助实现了显著提高发动机效率的技术，典型MPG增加了20%，从而节省了燃油消耗和二氧化碳排放。为了继续在嵌入式碳和产品性能方面实现逐年节省，显然迫切需要在小分子增材设计方面更加努力，并在制造和配方方面进行创新。此外，路博润的化学产品已超越了内燃机运输，并进入了汽车电气化和更广泛的终端市场，包括家庭和个人护理、工业和生命科学。事实上，化学是大多数产品的核心，据估计，超过96%的制成品都含有化学工业成分，使该行业成为英国经济的主要贡献者，也是通过创新实现变革的关键推动者。这一繁荣合作伙伴关系提案建立在与诺丁汉大学和沃里克大学的现有战略关系基础上，旨在解决一系列独特的商业主导研究挑战，这些挑战被视为路博润技术的“关键路径”，只有组建一个由学术界专家组成的多学科研究团队才能解决。这一合作伙伴关系将提供一个综合的愿景，设计更智能的分子，使用更好的化学和能源弹性过程。我们的愿景是尽可能使用连续加工来改变路博润及其他地区的化学品生产方式。我们的目标是最大限度地减少构建复杂分子所需的化学品、溶剂和加工步骤的数量。我们将通过利用原子高效催化来实现这一目标，以促进更具体的化学转化和更清洁的过程。通过将连续热化学和环境可接受的溶剂相结合，我们将创建一个工具包，该工具包能够将添加剂合成的各个方面从最初的发现转变为高价值分子的化学制造。

The UK has recently taken a bold step towards clean growth, consulting on ending the sale of conventional diesel and petrol passenger cars by 2035 and to realise a zero-emissions vehicle fleet by 2050. These ambitions are indeed bold however they place additional pressures on the automotive industry and its supply chain to innovate and highlight concerns about the onwards environmental viability of the existing automotive fleet. Placing aside the obvious scientific, environmental and technical hurdles that must be overcome to deliver mass electrification (assuming that is what is adopted and is the lowest environmental impact), these ambitions stimulate an awareness to reduce the impact of traditional internal combustion engines (ICE) in transportation across all scales. There is a pressing need to raise efficiencies, while reducing the integrated, life-long carbon footprint of the vehicle which prompts scrutiny on fuel efficiency, maintenance frequency, and indeed the impact of all ICE related consumables. To date Lubrizol products, which deliver a significant proportion of the fuel and engine oil additives that are used across all ICE platforms, have directly contributed to and help enable technology which gives notable increases in engine efficiency, in the order of 20% increase in typical MPG, which delivers savings in terms fuel consumption and CO2 emissions. To continue to deliver year-on-year savings in terms of embedded carbon and product performance there is a clear and urgent need to drive harder, in terms of small-molecule, additive design and to innovate in terms of manufacturing and formulation. Furthermore, Lubrizol chemistry reaches beyond ICE transportation and feeds into vehicle electrification and wider end markets, including home and personal care, industrial, and Life Sciences. Indeed, chemistry is at the heart of most products and it is estimated that over 96% of all manufactured goods have chemical industry content, making the industry a major contributor to the UK economy and a key facilitator of change through innovation. This Prosperity Partnership proposal builds on existing strategic relationships with University of Nottingham and University of Warwick to tackle a distinct series of business-led research challenges that are considered "critical path" in terms of Lubrizol technologies, which can only be addressed by assembling a multidisciplinary research team with experts drawn from academia. This partnership will deliver an integrated vision to design Smarter Molecules, using Better Chemistries, and Energy Resilient Processes. Our vision is to use, whenever possible, continuous processing to transform how chemicals are manufactured in Lubrizol and beyond. We aim to minimize the amount of chemicals, solvents and processing steps needed to construct complex molecules. We will achieve this by exploiting atom efficient catalysis to promote more specific chemical transformations and cleaner processes. By linking continuous thermal chemistry and environmentally acceptable solvents, we will create a toolkit with the power to transform all aspects of additive synthesis from initial discovery through to chemical manufacturing of high-value molecules.