CANCER & OTHER SERIOUS CONDITIONS AMONG PATIENTS

这项记录关联调查的目的是确定和 在选定的医疗诊断后量化癌症的风险 条件和某些外科手术。既往患者研究 某些医疗条件已经显示出显着的过度或 降低癌症风险。- 基于交配的名册的可用性 被诊断患有各种医学病症和/或接受 来自同一人群的登记数据提供了独特的机会， 开展具有成本效益的癌症病因学记录关联研究。队列 因特殊情况或外科手术住院的患者， 或列入出生或先天性疾病名册或登记册 已经成功地与人口癌症，死亡率， 以及瑞典、丹麦、美国、和加拿大 提出关于癌症病因学的新假设，以证实关于 与癌症风险相关的疾病或外科手术， 显示出与癌症风险的潜在保护性关联， 表明，尽管是间接的， 癌症风险，提供线索，病因机制， 致癌作用，并确定可能需要持续治疗的人群 因为癌症发生的风险增加了。

The objective of this record-linkage investigation is to identify and quantify the risk of cancer following the diagnosis of selected medical conditions and certain surgical procedures. Previous studies of patients with certain medical conditions have revealed significant excesses or decreased risks of cancer. - The availability of copulation-based rosters of patients diagnosed with various medical conditions and/or treated with registry data from the same population provides unique opportunities to conduct cost-efficient record-linkage studies of cancer etiology. Cohorts of patients hospitalized for specific conditions or surgical procedures, or included on rosters or registries of births or congenital disorders have been successfully linked with population-based cancer, mortality, and population registries in Sweden, Denmark, the U.S., and Canada to suggest new hypotheses about cancer etiology, to confirm hypotheses about disease or surgical procedure associations with cancer risk, to demonstrate potentially protective associations for cancer risk, to indicate, albeit indirectly, possible associations of medications with cancer risk, to provide clues as to etiologic mechanisms of carcinogenesis, and to identify populations that may require ongoing medical surveillance because of increased risk of cancer occurrence.