COLLABORATIVE INITIAL GLAUCOMA TREATMENT STUDY

本应用程序的目的是记录 佛罗里达大学作为一个有效和富有成效的 临床中心在拟议的多中心临床试验中，题为 “协作性青光眼初始治疗研究”(CIGTS)。这项研究是 目的评价开角型青光眼的早期治疗 更有效的方法是采用阶梯式的医疗方案或通过 手术方式。佛罗里达大学临床中心将 通过确定和招募符合条件的患者参与CIGTS， 按照CIGTS的规定实施治疗方案 协调中心，并在研究的操作手册中定义， 跟踪和留住研究患者，记录和转移研究 将数据提供给协调中心，并为将 展示CIGTS结果。 这份申请描述了佛罗里达大学 临床中心每年招收约13-26名患者，基础 根据在3个月内对患者资格进行的试点研究 句号。提供了我们的计划的详细信息，以确定、招募、跟踪 并留住这些患者，我们的意图是获得始终如一的高质量 关于治疗的视觉结果的数据，以及人员和 我们中心内的设施可用于执行本规定 CIGTS的操作手册。

The intent of this application is to document the ability of the University of Florida to participate as an effective and productive clinical center in the proposed multicenter clinical trial, entitled "Collaborative Initial Glaucoma Treatment Study" (CIGTS). This study's purpose is to evaluate whether initial treatment of open angle glaucoma is more effective by means of a stepped, medical regimen or by means of a surgical approach. The University of Florida's Clinical Center will participate in the CIGTS by identifying and recruiting eligible patients, administering the treatment regimen as assigned by the CIGTS's Coordinating Center and defined within the study's Manual of Operations, following and retaining study patients, recording and transferring study data to the Coordinating Center, and contributing to reports that will present the CIGTS results. This application describes the ability of the University of Florida's Clinical Center to enroll approximately 13-26 patients per year, based upon pilot studies of patient eligibility conducted during a 3 month period. Details are provided of our plans to identify, recruit, follow, and retain these patients, our intent to obtain consistently high quality data on the visual outcomes of treatment, and the personnel and facilities available within our center to carry out the provisions of the CIGTS's Manual of operations.