Cord blood stem cells for cerebral palsy

对发育中的大脑的损伤，无论是在怀孕期间还是在出生时，都是许多认知和运动障碍的根本原因，包括脑瘫。该项目将确定导致早产儿和足月儿发育性脑损伤的细胞途径，然后在不同的时间点应用脐带血干细胞，以评估它们在减少脑损伤方面的效果。该项目将为使用脐带血干细胞治疗高危婴儿提供信息。

Injury to the developing brain, whether sustained during pregnancy or at birth, is the underlying cause of many cognitive and motor disabilities, including cerebral palsy. This project will identify the cellular pathways that cause developmental brain injury in preterm and term infants, and then administer umbilical cord blood stem cells at different timepoints to assess their efficacy at reducing brain injury. This project will inform treatment with cord blood stem cells in high risk infants.