POSTMENOPAUSAL ESTROGEN/PROGESTIN INTERVENTIONS

在德克萨斯大学健康科学分校建立临床核心 在圣安东尼奥的中心。圣安东尼奥临床中心将招聘150人 围绝经期和绝经后妇女在一段时间内不得超过12个月。我们 建议比较口服雌激素治疗的效果 在没有微粒化黄体酮的情况下。建议的主要结果 参数包括评估：子宫内膜组织学、血脂和血糖 新陈代谢和症状学。其他建议的结果参数包括 心血管效应、凝血效应、胆囊炎效应 疾病和对骨密度的影响。

To establish a Clinical Core at the University of Texas Health Science Center in San Antonio. The San Antonio Clinical Center will recruit 150 peri- and postmenopausal women in a period not to exceed 12 months. We propose to compare the effects of oral estrogen treatments in the presence and in the absence of micronized progesterone. proposed primary outcome parameters include evaluation of: endometrial histology, lipid and glucose metabolism, and symptomatology. Other suggested outcome parameters include cardiovascular effects, effects on coagulation, effects on gallbladder disease and effects on bone density.