VISION RESEARCH CENTER

请求提供支持以建立核心设施和服务以支持 佛罗里达大学的视觉研究。我们建议建立 仪器车间、细胞/组织培养设施、生物化学/分子 生物学模块、EM/照片模块、计算服务和临床 研究开发模块。这些将支持在 视觉转导生物化学、视网膜退行性疾病、视网膜 基因表达，抗青光眼和散瞳药物开发，角膜创伤 愈合，黄斑变性，视网膜细胞通讯，分子基础 对于色觉异常，早期发现青光眼，视网膜病变 早产、眼黑色素瘤、先天性内斜视等研究。 通过这些核心设施，我们预计： 1.提高各部门科研人员的能力 佛罗里达大学进行视觉研究。堆芯 设施将支持现有的基础和临床眼科研究工作 并促进新的计划。 2.促进VISION中的协作和多学科研究 研究。协作、沟通和思想交流以及 我们的调查人员在很大程度上已经具备了专业知识 各部门。共享的支助设施将用于：(A)进一步 增强社区意识、共同目标和宗旨，以及(B) 增加对高优先级问题的跨学科研究 在视觉科学领域。

Support is requested to establish Core facilities and services to support research in vision at the University of Florida. We propose establishing an Instrument Shop, Cell/Tissue Culture facility, Biochemistry/Molecular Biology module, EM/Photograph module, Computing Services, and a Clinical Research Development module. These will support studies in the biochemistry of visual transduction, retinal degenerative disease, retinal gene expression, antiglaucoma an mydriatic drug development, corneal wound healing, macular degeneration, retinal cell communication, molecular basis for anomalous color vision, early detection of glaucoma, retinopathy of prematurity, ocular melanoma, congenital esotropia, and other studies. By means of these Core facilities we expect: 1. To enhance the ability of researchers in various departments at the University of Florida to perform studies in vision research. Core facilities will bolster existing basic and clinical eye research efforts across the campus and facilitate new initiatives. 2. To promote collaborative and multidisciplinary studies in vision research. Collaboration, communication, and interchange of ideas and expertise already exist to a great extent among our investigators and departments. The shared support facilities will serve (a) to further bolster the sense of community, common goals and objectives, and (b) to increase the amount of interdisciplinary research on high-priority problems in the visual sciences.