CONTINUING STUDIES OF CAT ALLERGY

猫提取物可能含有毛皮，毛发，皮屑，浓缩猫洗液， 唾液或这些物质的任何混合物。 由于来源的可变性 材料，蛋白质和非Fel d I过敏原水平的差异已被 检测到标准化猫提取物导致了发展 和实施额外的实验室方法， 参比制剂，以帮助表征这些 萃取物 猫浸提液效价的当前放行检测是放射性的 免疫扩散试验测量Fel d I含量， 猫过敏原。斑点放射免疫电聚焦（BRIEF） 证明了简单等电聚焦（IEF）在 标准化猫非Fel d I过敏原的定性检测 萃取物通过IEF表征猫提取物已被证明是一种 敏感患者中临床活性的可靠指标 对非Fel d I过敏原。正在开展活动， 标准化猫提取物作为猫毛或猫毛皮产品。陪同 标记将指示毛皮中存在额外的非Fel d I 产品，从而提高这些新产品的安全性， 消除与源材料术语有关的混淆。

Cat extracts may contain pelt, hair, dander, concentrated cat wash, saliva, or any mix of these materials. Due to variability in source material, differences in protein and non-Fel d I allergen levels have been detected. The standardization cat extracts has resulted in the development and implementation of an additional laboratory method and accompanying reference preparations to assist in the characterization of these extracts. The current release test for potency of cat extracts is a radial immunodiffusion test that measures Fel d I content, one of the primary allergens of cat. Blotted RadioImmuno ElectroFocusing (BRIEF) demonstrated the value of simple IsoElectric Focusing (IEF) in the qualitative detection of non-Fel d I allergens in standardized cat extracts. The characterization cat extracts by IEF has proven to be a reliable indicator of clinical activity in patients that are sensitive to non-Fel d I allergens. Activities are in progress to designate standardized cat extracts as cat hair or cat pelt products. Accompanying labeling will indicate the presence of additional non-Fel d I in the pelt products, thereby enhancing the safety of these new products and eliminating confusion related to source material terminology.