HIGH RESOLUTION IMAGE DIGITIZATION AND ANALYSIS SYSTEM

这是一个申请资金购买高分辨率图像 数字化和分析系统将用于实验， 这项研究正在爱荷华州大学进行。 设备 要求包括一个数码相机，一个成像工作站，一个磁盘 服务器和多个输出设备。 拟议的文书将是 位于爱荷华州大学的图像分析设施，这是一个 大学核心设施提供给所有教职员工， 由一位科学可视化专家完成。 超过100个不同的研究小组参与了广泛的 研究项目利用图像处理和图形建模， 图像分析设施中的系统。 其中，7大 用户参与了11个不同的PHS资助项目， 在分辨率和灵敏度方面受到严格限制， 实验图像测量的过时设备，他们是 目前使用。 所要求的成像和图形系统已经 精心挑选，以补充现有的能力， 满足这群研究人员和其他研究人员的需求， 计划扩展到这项技术。 将立即受益于 已提供所需设备。 塔尔曼正在量化和可视化 注射的药剂扩散到大鼠的背侧迷走神经复合体中。 Andreasen正在绘制多巴胺能和血清素能受体系统， 死后精神分裂症患者额叶切除和正常人的大脑 华纳 是观察和测量不同麻醉剂对 中风患者的血液流动 Kultas-Ilinsky正在量化GABA 与神经结构结合。 托德正在测量麻醉的效果 对血流的影响 弗兰茨正在监测伤口愈合实验。 贾尼是 近距离放射治疗植入物的等剂量场成像。 支持 购买拟议的仪器将允许分析， 目前在爱荷华州的大学。

This is an application for funds to purchase a high resolution image digitizing and analysis system to be used in experiments vital to research being performed at the University of Iowa. The equipment requested includes a digital camera, one imaging workstation, a disk server and several output devices. The proposed instrument will be housed in the University of Iowa Image Analysis Facility, which is a university core facility available to all faculty and staff and operated by a scientific visualization specialist. Over one hundred different research groups involved in a wide range of research projects utilize the image processing and graphics modelling systems housed in the Image Analysis Facility. Of these, seven major users are involved in a total of 11 different PHS funded projects which are severely restricted in the resolution and sensitivity of their experimental image measurements by the outdated equipment they are currently using. The requested imaging and graphics system has been carefully selected to complement the existing capabilities and to fulfill the needs of this group of researchers, and others who are planning to expand into this technology. The descriptions of projects which would benefit immediately from the equipment requested is provided. Talman is quantizing and visualizing diffusion of injected agents into the dorsal vagal complex of rats. Andreasen is mapping dopaminergic and sertoninergic receptor systems in post mortem schizophrenic, lobotomized, and normal human brains. Warner is visualizing and measuring the effects of different anesthetics on blood flow in stroke victims. Kultas-Ilinsky is quantifying GABA binding to neurostructures. Todd is measuring the effects of anesthesia on blood flow. Frantz is monitoring wound healing experiments. Jani is imaging the isodose fields of brachytherapy implants. Support for the purchase of the proposed instrument would allow for analysis not currently possible at the University of Iowa.