National studies of kidney disease in childhood and adolescence

儿童肾脏疾病是罕见的，但对家庭和儿童以及医疗服务的要求很高。大部分的工作量是在专科儿童医院管理的，需要透析和移植设施。如果能够通过收集整个英国人口的临床信息、血液和DNA样本，更系统地研究导致肾衰竭的疾病，那么就可以设计出更好的预防肾衰竭的策略。本研究将持续收集2种此类疾病的信息，并得到所有领先的英国肾脏组织的大力支持。这将是第一次整理如此全面的疾病信息，并将为以同样全面的方式研究更多的肾脏疾病建立基础设施。

Kidney disease in children is rare, but highly demanding, both for the families and children, and for the medical services. The majority of the workload is managed in specialist children s hospitals, and requires facilities for dialysis and transplantation. If the diseases that lead to kidney failure could be studied more systematically, by collecting clinical information, blood and DNA samples from the whole UK population, then better strategies for preventing kidney failure could be devised. This study will collect information from 2 such diseases, in an ongoing basis, and has the robust support of all the leading UK kidney organisations. This will be the first time such comprehensive disease information has been collated, and will set up an infrastructure for many more kidney diseases to be studied in the same comprehensive way.