Biomarkers to predict severity in dengue infection

登革热是一种在热带和亚热带地区感染蚊子的病毒。它可能导致严重的出血热，除非在医院接受治疗，否则可能是致命的。在早期阶段，无法判断哪些患者将出现更严重的症状，应该入院治疗。在疫情期间，几乎可以同时发生数千例病例，并完全使医院系统不堪重负。这项研究旨在开发一种简单的疾病严重程度预测指标，允许高危患者入院，而低风险患者可以在家中进行管理。

Dengue is a mosquito bourne viral infection of the tropics and subtropics. It can lead to a severe haemorrhagic fever that can be fatal unless treated in hospital. At the early stages it is impossible to judge which patients are going to suffer the more severe symptoms and should be admitted to hospital. During epidemics literally thousands of cases can occur at the same time and completely overwhelm the hospital systems. This research aims to develop a simple predictor of disease severity which would allow the high risk patients to be admitted to hospital whilst those at lower risk could be managed at home.