MAGNESIUM METABOLISM IN HUMAN AND BIOLOGICAL SYSTEMS

不到1%的全身镁存在于外周 血 我们开发了一种测定血液中镁含量的方法 单核细胞作为细胞内镁和/或全身指标 镁状态 血镁状态（血浆和红细胞 镁浓度和单核血细胞含量） 在甲状旁腺疾病患者中进行评估。 结果表明 原发性甲状旁腺功能亢进的患者， 红细胞中镁的浓度和 镁在单核血细胞与正常人相比。 慢性甲状旁腺功能减退症患者则相反。 血浆镁浓度无显著变化， 组

Less than 1% of the total body magnesium is present in the peripheral blood. We developed an assay to determine the magnesium content of blood mononuclear cells as an index for intracellular magnesium and/or total body magnesium status. The blood magnesium status (plasma and red cell concentrations and mononuclear blood cell content of magnesium) was assessed in patients with parathyroid disease. The results show that patients with primary hyperparathyroidism have a decrease in the concentration of magnesium in red blood cells and in the content of magnesium in mononuclear blood cells compared with normal individuals. Patients with chronic hypoparathyroidism showed the opposite results. There was no significant change in plasma magnesium concentration among the groups.