Mechanisms underlying limb regeneration in an adult vertebrate

像这样的成年火蜥蜴能够在完全恢复功能的情况下再生他们的四肢。火蜥蜴是如何再生四肢的？为什么我们不能这样做呢？我们的研究正在研究肢体再生的一些关键成分，特别是那些在火蜥蜴身上发现的，而不是在我们身上发现的那些。火蜥蜴和人类基因组项目为识别这些成分提供了重要资源。如果我们了解它们是如何工作的，这将为试图增强我们自身的再生能力提供新的动力。

Adult salamanders such as the newt are able to regenerate their limbs with complete recovery of function. How does a salamander regenerate its limb and why can we not do this? Our research is studying some of the critical components that underly limb regeneration, and in particular the ones that are found in salamanders and not in us. The salamander and human genome projects provide important resources for identifying such components. If we understood how they worked this would provide a new impetus for trying to enhance our own abilities to regenerate.