REGIONAL LEFT VENTRICULAR ASYNCHRONY IN CORONARY ARTERY DISEASE

左室整体舒张和舒张充盈异常， 许多左心室功能正常的冠心病患者 收缩功能 局部室壁运动正常的患者， 通过放射性核素血管造影评估的舒张期充盈与 舒张期收缩 在可见明显区域壁的患者中 运动异常，收缩期痉挛导致更大的损害， 整体舒张充盈，而舒张功能障碍的严重程度直接 与左心室充盈的时间延迟有关。 这些数据 表明非同步左心室收缩功能是一种 左室舒张功能总体异常的决定因素。

Global left ventricular relaxation and diastolic filling is abnormal in many patients with coronary artery disease who have normal left ventricular systolic function. In patients with normal regional wall motion, abnormal diastolic filling, assessed by radionuclide angiography, is related to diastolic asynchrony. In patients with visually apparent regional wall motion abnormalities, systolic asynchrony results in greater impairment in global diastolic filling, and the severity of asynchrony is directly related to the temporal delay in left ventricular filling. These data indicate that asynchronous left ventricular systolic function is a determinant of global abnormalities in left ventricular diastolic function.