IMPROVED LEFT VENTRICULAR FUNCTION, AT REST AFTER CORONARY ARTERY BYPASS

许多冠状动脉疾病患者表现出心肌梗死的证据， 静息时缺血，如舒张期充盈异常和局部缺血 这两种疾病在成功经皮穿刺后都可能逆转。 经腔冠状动脉成形术 进一步的证据是， 局部和整体心室收缩功能， 冠状动脉搭桥手术 我们观察到左心室有明显改善， 28例无既往病史的患者静息时心室射血分数 心肌梗死患者在接受放射性核素血管造影检查之前 冠状动脉搭桥手术后6个月。 此外，定量 区域分析表明，在静息状态下， 在运动前发生缺血的区域进行手术 操作 这些数据支持了冠状动脉疾病可能 患者在静息状态下存在亚临床左心室缺血 冠状动脉血流恢复后可逆的疾病。

Many patients with coronary artery disease manifest evidence for myocardial ischemia at rest, such as diastolic filling abnormalitites and regional asynchrony, both of which may be reversed after successful percutaneous transluminal coronary angioplasty. Further evidence is the improvement in regional and global ventricular systolic function that occurs after coronary bypass operation. We observed a significant improvement in left ventricular ejection fraction at rest in 28 patients without previous myocardial infarction who were studied by radionuclide angiography before and 6 months after coronary bypass surgery. Moreover, quantitative regional analysis demonstrated improved regional function at rest after operation in those regions developing ischemia during excercise before operation. These data support the concept that may coronary artery disease patients have subclinical left ventricular ischemia under resting conditions which is reversible after restoration of coronary flow.