A global registry of women affected by COVID-19 in pregnancy, understanding natural history to guide treatment and prevention

目前的冠状病毒爆发（COVID-19）规模正在扩大，将影响全球数百名孕妇。MERS、SARS和其他冠状病毒感染导致孕妇比非孕妇病情更严重，死亡率、流产率、早产率和早产儿率更高。已有18名妇女在怀孕后三分之一期间感染COVID-19的病例报告。目前尚缺乏关于COVID-19在怀孕各个阶段（如怀孕早期）的影响及其对分娩前后母亲和婴儿健康影响的信息。这项研究将收集世界各地怀孕期间COVID-19感染的信息，以指导治疗和如何防止传播。我们将建立一个怀孕期间受COVID-19影响的妇女数据库（登记册）。案例将由欧洲、中国、香港和美国的合作者添加。医护人员将把这些妇女、她们的怀孕情况和婴儿的信息输入一个安全的网页，登记处的每周报告将在网上公布。这个报告病例的数据库将允许医疗保健专业人员，研究人员和政策制定者计划在这次疫情中以及未来的预防和治疗。

The current coronavirus outbreak (COVID-19) is growing in magnitude and will affect hundreds of pregnant women globally. MERS, SARS, and other coronovirus infectionscause more severe illness in pregnant women than non-pregnant women, with higher rates of deaths, pregnancy loss, premature births and small-for-dates babies.There have been case reports of 18 women affected by COVID-19 in the later third of their pregnancy. There is a lack of information on the effect of COVID-19 at all stages of pregnancy e.g. early pregnancy and its effect on mothers’ and babies’ health before and after delivery.This study will gather information from around the world of COVID-19 infection during pregnancy to inform treatment and how to prevent spread.We will set up a database (register) of women affected by COVID-19 in pregnancy. Cases will be added by collaborators across Europe, China, Hong Kong and the USA. Information about the women, their pregnancies and babies will be entered by healthcare professionals into a secure web page.Weekly reports from registery will be published online. This database of reported cases with detailed pregnancy outcomes will allow healthcare professionals, researchers and policy makers to plan prevention and treatments in this outbreak, and in the future.