Determining the causes of congenital malformation

出生缺陷占活产婴儿的3%，占出生前夭折胎儿的78%。这些缺陷的原因在很大程度上是未知的。有些是由于遗传因素，有些是由于环境压力，还有一些是由于遗传和环境对胎儿发育的综合影响。本研究旨在找出导致出生缺陷的遗传和环境因素，以期减少出生缺陷的发生。

Birth defects are present in 3% of live births and account for some of the 78% of fetuses lost before birth. The causes of these defects are largely unknown. Some are due to genetic factors, some to environmental stresses, and others to a combination of genetic and environmental influences on fetal development. This research aims to identify the genetic and environmental factors that cause birth defects with the anticipation that the occurrence of birth defects may be reduced.