TOMOGRAPHIC RADIONUCLIDE ANGIOGRAPHY

放射性核素血管造影常用于评估左心室 冠状动脉疾病患者的心脏功能。 但由于 重叠区域和应用平面、两个- 三维图像来评估三维器官的功能， 断层扫描灌注缺损与平面区域 室壁运动异常可能不准确。 本研究 比较了22例慢性前列腺炎患者的放射性核素断层扫描检查结果， 冠状动脉疾病，也接受了平面放射性核素 动脉造影 分析了平面和断层室壁运动 由设盲阅片者定性为正常/运动功能减退，严重 运动功能减退或运动不能/运动障碍。 体层摄影放射性核素 血管造影图像显示在水平方向的3个连续切片中 长轴、垂直长轴和短轴视图。 其中， 分析了110个区域，平面和断层血管造影研究 在84个（76%）区域提供了一致的室壁运动信息。 所有 67个区域（100%）被断层扫描确定为正常或运动减退， 通过平面研究也是正常或运动减退。 仅3/14（21%）为重度 通过断层扫描确定运动功能减退区域为严重运动功能减退 通过平面放射性核素血管造影; 9例被指定为正常/运动减退 运动不能/运动障碍2例。 同样，29人中只有14人（48%） 运动不能/运动障碍区域被确定为 通过平面研究确定运动不能/运动障碍; 8例被分配 正常/运动功能减退，7例为严重运动功能减退。 相比之下， 没有被指定为重度运动功能减退或运动不能/运动障碍的区域 通过平面放射性核素血管造影， 断层扫描显示正常/运动功能减退。 因此，断层放射性核素 血管造影检出大量室壁运动异常而漏诊 通过平面成像，而没有平面严重运动功能减退或 运动不能/运动障碍性局部室壁运动异常被遗漏， 层析成像研究 在没有黄金标准的情况下，这些数据 表明放射性核素断层造影术可以识别更多 功能障碍的心肌区域比平面成像。

Radionuclide angiography is frequently used to assess left ventricular function in patients with coronary artery disease. However, due to overlapping regions and the inherent limitation of applying planar, two- dimensional images to assess the function of a three-dimensional organ, direct correlation of tomographic perfusion defects with planar regional wall motion abnormalities may not be accurate. In this study, we compared tomographic radionuclide studies among 22 patients with chronic coronary artery disease who also had undergone planar radionuclide angiography. Both planar and tomographic wall motion were analyzed qualitatively by blinded readers as normal/hypokinetic, severely hypokinetic, or akinetic/dyskinetic. Tomographic radionuclide angiography images were displayed in 3 contiguous slices in horizontal long-axis, vertical long-axis and short-axis views. Among a total of 110 regions analyzed, planar and tomographic angiography studies provided concordant wall motion information in 84 (76%) regions. All 67 regions (100%) identified as normal or hypokinetic by tomography were also normal or hypokinetic by planar studies. Only 3 of 14 (21%) severe hypokinetic regions by tomography were identified as severe hypokinetic by planar radionuclide angiography; 9 were assigned normal/hypokinetic and 2 akinetic/dyskinetic. Similarly, only 14 of 29 (48%) akinetic/dyskinetic regions by tomography were identified as akinetic/dyskinetic by planar studies; 8 were assigned normal/hypokinetic and 7 as severe hypokinesis. In contrast, there were no regions that were assigned severe hypokinesis or akinesis/dyskinesis by planar radionuclide angiography that were interpreted as normal/hypokineitc by tomography. Therefore, tomographic radionuclide angiography detected a large number of wall motion abnormalities missed by planar imaging while none of planar severe hypokinetic or akinetic/dyskinetic regional wall motion abnormalities were missed by tomographic studies. In the absence of a gold standard, these data suggest that tomographic radionuclide angiography may identify more dysfunctional myocardial regions than planar imaging.