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EFFECT OF IGF-1 ON MALNOURISHED CHILDREN WITH CYSTIC FIBROSIS

EFFECT OF IGF-1 ON MALNOURISHED CHILDREN WITH CYSTIC FIBROSIS
IGF-1 对患有囊性纤维化的营养不良儿童的影响
批准号:
5225659
负责人:
JOHN C BUCUVALAS
金额:
$0.0万
依托单位:
--
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
囊性纤维化(CF)儿童的营养不良,由以下原因引起: 慢性肺疾病的复杂相互作用,能量增加 消耗、吸收不良和复发性感染。 生长刺激 肽促进营养不良的患者的食欲。 我们 目的是检验以下假设: 生长因子-I(IGF-1),它有助于合成代谢的性质, 生长激素,将导致增强线性增长,增加瘦肉 体重和改善肺功能的营养受损 儿童CF
英文摘要
Malnutrition in children with cystic fibrosis (CF), results from a complex interaction of chronic pulmonary disease, increased energy expenditure, malabsorption, and recurrent infection. Growth-stimulating peptides promote anabolism in nutritionally compromised patients. Our goal is to test the following hypothesis: Treatment with insulin-like growth factor-I (IGF-1), which subserves the anabolic properties of growth hormone, will result in enhanced linear growth, increased lean body mass and improved lung function in nutritionally compromised children with CF.
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Calcineurin Inhibitor Minimization And Foxp3+ Tregs Post-Transplant
  • 批准号:
    7829439
  • 项目类别:
  • 资助金额:
    $47.79万
  • 财政年份:
    2009
  • 负责人:
    JOHN C BUCUVALAS
  • 依托单位:
Calcineurin Inhibitor Minimization And Foxp3+ Tregs Post-Transplant
  • 批准号:
    7942967
  • 项目类别:
  • 资助金额:
    $48.1万
  • 财政年份:
    2009
  • 负责人:
    JOHN C BUCUVALAS
  • 依托单位:
BILIARY ATRESIA RESEARCH CONSORTIUM DATABASE
BILIARY ATRESIA STUDY (BASIC)