CATHETER-MOUNTED INTRA-CARDIAC ULTRASOUND IMAGING ARRAY

Creare建议开发一种用于心内解剖特征成像的超声系统。 我们的系统将包含一种新型的导管安装换能器阵列，该阵列由安装在导管尖端上的共形二维阵列中排列的多个单独的换能器元件组成。该系统将为临床医生提供一个强大的新的诊断工具，提高了医生看到心房和心室内部的实时超声图像的能力。该图像可能有助于引导器械放置和展开（如支架和球囊），可视化细微特征（如射频消融军团），并对先天性心脏病患者进行成像。在该项目的第一阶段，将制造一个原型，安装在导管上的心内换能器阵列，并在一系列体外测试中对其性能进行评价。在第二阶段，Creare将建立一个成像导管，并在临床环境中安装该系统。 该系统将用于成像细微的解剖特征和消融军团的形成。拟议的商业应用：临床有效的心内成像导管的商业意义是巨大的。 我们的商业化合作伙伴承诺寻求成功完成该项目所产生的技术许可证，这就是证明。

Creare proposes to develop an ultrasound system for imaging intracardiac anatomic features. Our system will incorporate a novel catheter-mounted transducer array comprised of a number of individual transducer elements arranged in a conformal two- dimensional array mounted on the catheter tip. This system will provide the clinician with a powerful new diagnostic tool that increases the capability of the physician to see a real-time ultrasound image of the inside of both the atria and ventricles. This image will potentially assist in guiding device placement and deployment (such as stents and balloons), visualizing subtle features (such as radio frequency ablation legions), and imaging patients with congenital heart defects. During Phase I of this project, a prototype, catheter-mounted intracardiac transducer array will be fabricated and its performance evaluated in a series of in vitro tests. In Phase II, Creare will build an imaging catheter and install the system in a clinical setting. The system will be used to image subtle anatomical features and the formation of ablation legions. PROPOSED COMMERCIAL APPLICATIONS: The commercial significance of a clinically effective intracardiac imaging catheter is tremendous. This is evidenced by the commitment of our commercialization partner to seek a license to the technology resulting from successful completion of this project.