SHELTERED ANIMAL HOUSING FOR REGIONAL PRIMATE CENTER

拟议的建设为非人类灵长类动物（NHPs）提供了新的创新庇护住房，并将取代目前容纳灵长类动物生产群体的30年历史的室外开放式畜栏。有很多原因导致我们建造替代住房来取代开放式畜栏。首先，计划性增长需要扩大生产群体。自1994年以来，俄勒冈地区灵长类动物研究中心（ORPRC）的研究项目几乎翻了一番（就研究经费和分配给研究项目的NHPs数量而言）。由于几个原因，预计这种增长速度将继续下去。1)特别拨款以加强生产克隆衍生NHPs的计划，2)扩大传染病研究，以及3)将R.S. Dow神经科学研究所迁至ORPRC校园。通过将开放的自由放养畜栏转换为20个庇护所住房单元（每个单元可容纳25-30个nph），在相同数量的空间内，生产动物的数量可以从100-150增加到500-600。其次，美国农业部的规定和标准不鼓励在露天畜栏中饲养动物。庇护设施将确保动物在符合高动物护理标准的环境中饲养和繁殖。封闭的庇护住房单元将：1)允许有效和彻底的动物环境日常卫生，20允许安全进入动物，3)允许社会互动的选择，4)将遵守所有NIH指导方针，AAALAC建议，以及其他适用的联邦和地方法规。第三，希尔斯伯勒市（ORPRC所在的地方政府）的总体规划规定，现有的畜栏必须退役，并且不开发额外的“开放式”动物收容所。我们的五年计划将一个2英亩的畜栏转换成包含20个庇护住房设施的区域。该提案要求为开始第一阶段的建设提供资金；请拨资金建造8个庇护住房单元，每套可容纳25-30名保健服务人员。

The proposed construction provides new innovative sheltered housing for non-human primates (NHPs) and will replace the 30 year old outdoor open corrals that presently house our primate production colony. There are a number of reasons that have led us to construct alternative housing to replace the open corrals. First, programmatic growth necessitates the expansion of the production colony. The research program at the Oregon Regional Primate Research Center (ORPRC) has nearly doubled (in terms of research dollars and number of NHPs assigned to research projects) since 1994. This rate of growth is expected to continue for several reasons. 1) Special funding to enhance the program to produce clonally- derived NHPs, 2) The expansion in infectious disease research, and 3) The relocation of the R.S. Dow Neurological Sciences Institute to the ORPRC campus. By converting the open free ranging corrals into 20 shelter housing units (each holding from 25-30 NPHs), the number of production animals can be increased from 100-150 to 500-600 in the same amount of space. Second, USDA regulations and standards discourage raising animals in an open outdoor corral setting. The sheltered facilities will assure that animals are housed and bred in an environment that meets high animal care standards. The enclosed sheltered housing units will: 1) permit efficient and thoroughly daily sanitation of the animals' environment, 20 allow safe access to the animals, 3) permit options of social interactions, and 4) will comply with all NIH guidelines, AAALAC recommendations, and other applicable federal and local regulations. Third, the City of Hillsboro's (the local government in which ORPRC resides) MasterPlan mandates that existing corrals be decommissioned and no additional "open" animal housing be developed. Our five year plan coverts one of our 2-acre corrals into the area that contains the 20 sheltered housing facilities. The proposal requests funds to begin the first phase of construction; funds are requested to construct 8 sheltered housing units that will hold 25-30 NHPs each.