CORE--BIOSTATISTICS

口腔癌症研究中心的生物统计学核心设施将 为所有调查人员提供服务和协作。这将是 加强每个项目，更好地确保最有效的研究设计， 所有符合条件的患者的前瞻性数据收集，计算机数据库 管理和使用统计方法，以便综合和分析 数据。核心将：1)提供所有项目的统计设计， 2)提供所有已确定的预期数据收集和数据输入 经组织学证实的口腔鳞状细胞癌患者 腔和咽，以及数据的质量保证，3)提供 协调计算机数据库管理系统，获取和集成 来自所有项目和核心的数据，4)提供生物统计分析 假设，5)与调查人员合作开发和 确定多变量、跨项目分析的优先顺序，以及6)开发和 采用统计学方法进行多种生物标记的分析 侵袭性皮肤癌与非侵袭性皮肤癌研究。

The Biostatistics Core Facility for the Oral Cancer Research Center will provide services and collaboration to all investigators. This will enhance each project, better ensure the most effective design of studies, prospective data collection on all eligible patients, computer data base management and use of statistical methods for integration and analyses of data. The Core will: 1) provide the statistical design of all projects, 2) provide prospective data collection and data entry for all identified patients with histologically confirmed squamous cell carcinoma of the oral cavity and pharynx, and quality assurance of data, 3) provide a coordinated computer database management system to obtain and integrate data from all projects and cores, 4) provide biostatistical analyses of hypotheses, 5) work collaboratively with investigators to develop and prioritize multivariate, across project analyses, and 6) to develop and adapt statistical methods for analyses of multiple biologic markers in aggressive vs. non-aggressive skin cancer research.