Development of a humanised antibody for treatment of cancer and stroke
Development of a humanised antibody for treatment of cancer and stroke
批准号:
nhmrc : 1038334
负责人:
Prof Andrew Scott
金额:
$26.68万
依托单位国家:
澳大利亚
项目类别:
NHMRC Development Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2013-12-31
中文摘要
PDGF-CC蛋白在血管发育中起着关键作用,并与癌症的发展和急性中风的衰弱后果有关。路德维希癌症研究所的研究人员开发了一种新的抗pdgf - cc抗体。拟议的研究计划将产生数据和临床试剂,使抗pdgf - cc抗体的主要候选抗体商业化,并最终在癌症和中风患者中进行临床评估。
英文摘要
The protein PDGF-CC has a critical role in blood vessel development, and is implicated in the development of cancer, and the debilitating consequences of acute stroke. Researchers in the Ludwig Institute for Cancer Research have developed novel anti-PDGF-CC antibodies. The research program proposed will generate data and clinical reagents that will enable a lead candidate anti-PDGF-CC antibody to be commercialised, and ultimately evaluated clinically in cancer and stroke patients.
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会议论文
Developmental Therapeutics for the Treatment of Gastrointestinal Cancers
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批准号:nhmrc : GNT1092788
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项目类别:Programs
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资助金额:$521.54万
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财政年份:2016
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负责人:Prof Andrew Scott
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依托单位:
Developmental Therapeutics for the Treatment of Gastrointestinal Cancers
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批准号:nhmrc : 1092788
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项目类别:Program Grants
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资助金额:$359.58万
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财政年份:2016
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负责人:Prof Andrew Scott
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依托单位:
Molecular Imaging and Therapy of Cancer
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批准号:nhmrc : GNT1084178
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项目类别:Practitioner Fellowships
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资助金额:$47.27万
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财政年份:2015
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负责人:Prof Andrew Scott
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依托单位:
Molecular Imaging and Therapy of Cancer
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批准号:nhmrc : 1084178
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项目类别:Practitioner Fellowships
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资助金额:$32.9万
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财政年份:2015
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负责人:Prof Andrew Scott
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依托单位:
Development of a humanised antibody for treatment of cancer and stroke
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批准号:nhmrc : 1075898
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项目类别:Development Grants
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资助金额:$16.19万
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财政年份:2014
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负责人:Prof Andrew Scott
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依托单位:
Therapeutic Strategies in Epithelial Cancer Through Signalling Inhibition of the Epidermal Growth Factor Receptor.
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批准号:nhmrc : 234709
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项目类别:NHMRC Project Grants
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资助金额:$9.09万
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财政年份:2003
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负责人:Prof Andrew Scott
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依托单位:
Tumor specific variants of the EGFR: Characterization, function and target for immunotherapy.
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批准号:nhmrc : 191500
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项目类别:NHMRC Project Grants
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资助金额:$9.39万
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财政年份:2002
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负责人:Prof Andrew Scott
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依托单位:
A tumor specific variant of the EGFR: Characterization and target for immunotherapy.
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批准号:nhmrc : 164814
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项目类别:NHMRC Project Grants
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资助金额:$5.71万
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财政年份:2001
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负责人:Prof Andrew Scott
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依托单位:
海外基金