ENERGETICS OF THE INTERACTION BETWEEN WATER, MEMBRANES AND MACROMOLECULES

我们已经确定了水合热力学， 单烷基族的_Ho298、_So298和_Go298 使用电喷雾的氨离子，C1-C8和1-3C1 电离-平衡气相离子分子反应。这个 根据平衡计算了水化热力学数值。 离子源水部分条件下测得的常量 压力范围在0到100 mtorr之间，相当于0-1% 总源压和离子源温度范围在 23和85摄氏度。我们的研究清楚地表明，1)增加第一个 水对裸离子的放热作用比向离子中加入 第三步；2)向单烷基铵中加第一水 离子约2千卡/摩尔更有利于 单甲基比单丁基少，相对较少 通过进一步增加烷基链长来改变；3)添加 一是水与单甲基铵离子的比例约为3千卡/摩尔 对于三甲基的情况更有利。此外，还增加了 丙基铵的第一次加水大约要多1.5千卡/摩尔 比在三甲基中加第一水更有利 铵盐

We have determined hydration thermodynamics, _Ho298, _So298, and _Go298, for a family of monoalkyl ammonium ions, C1-C8 and 1-3 C1, using the electrospray ionization-equilibrium gas phase ion molecule reactions. The hydration thermodynamic values were calculated from equilibrium constants measured under conditions of ion source water partial pressures ranging between 0 and 100 mtorr, equivalent to 0-1% of total source pressure, and ion source temperatures ranging between 23 and 85oC. Our study clearly shows that 1) addition of the first water to a bare ion is apprecibly more exothermic than addition of the third; 2) addition of the first water to monoalkyl ammonium ions is about 2 kcal/mole more favorable for the case of monomethyl than for monobutyl and that there is relatively little change by further increases of alkyl chain length; 3) addition of the first water to monomethyl ammonium ions is about 3 kcal/mole more favorable for the case of trimethyl. Furthermore, addition of the first water to propyl ammonium is about 1.5 kcal/mole more favorable than the addition of the first water to trimethyl ammonium