DISORDERS OF LIPID METABOLISM

该方案用于获得血浆脂蛋白和载脂蛋白， 支持格拉德斯通研究所的一些研究项目， 心血管疾病 这些项目包括与下列方面有关的调查： 血浆脂蛋白代谢、动脉粥样硬化和神经细胞功能。 目前的项目旨在测试假设，主要 三种蛋白质之间的结构差异（氨基酸序列差异） 载脂蛋白-E的主要亚型解释了不同的三级 影响脂蛋白代谢中同种型功能的结构。

This protocol is used to obtain plasma lipoproteins and apolipoproteins to support a number of research projects in the Gladstone Institute of Cardiovascular Disease. The projects include investigations related to plasma lipoprotein metabolism, atherosclerosis, and neural cell function. The current project is designed to test the hypothesis that primary structure differences (amino acid sequence differences) between the three major isoforms of apolipoprotein-E account for different tertiary structures that affect isoform function in lipoprotein metabolism.