课题基金 / 基金详情

PIVOTAL EFFICACY STUDY OF INHIBITION OF GASTRIC ACID SECRETION BY PANTOPRAZOLE

PIVOTAL EFFICACY STUDY OF INHIBITION OF GASTRIC ACID SECRETION BY PANTOPRAZOLE
泮托拉唑抑制胃酸分泌的关键功效研究
批准号：
6297819
负责人：
JOSEPH R PISEGNA
金额：
$0.19万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6297819
关键词：
Zollinger Ellison syndrome antiulcer drug benzimidazoles clinical research clinical trials drug screening /evaluation endocrine neoplasm gastric acid gastric juice inhibitor gastrointestinal disorder chemotherapy human subject human therapy evaluation intravenous administration secretion stomach surgery

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中文摘要
翻译
目的是确定静脉注射(IV)的方案。 使用能够减少和维持胃酸的潘托拉唑 Zollinger-Ellison患者的分泌量低于10mEq/小时 伴有或不伴有多发性内分泌肿瘤的综合征-I型(男性- I)未接受过胃大部切除术且小于 5 mEq/小时在有或没有男性的ZE患者中-I有 接受了胃大部切除术，安全无大碍。
英文摘要
The objective is to identify the regimens of intravenously (IV) administered pantoprazole that would decrease and maintain acid secretion at less than 10mEq/hr in patients with Zollinger-Ellison syndrome (ZES) with or without multiple endocrine neoplasia-type I (MEN- I) syndrome who have not undergone partial gastrectomy and at less than 5 mEq/hr in those patients with ZES with or without MEN-I who have undergone partial gastrectomy and to minor safety.
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