ARRHYTHMIAS & CHAOS

该项目使用分子和组织化学技术来 检查性腺功能丧失(循环性腺功能丧失 类固醇)影响生长因子、生长因子的表达 与学习和记忆有关的受体和酶 以及在年龄和疾病相关的认知能力下降。我的用法 超级计算中心将主要用于搜索和检索 用于诸如基因库等核酸数据库的核酸序列，以 执行序列比对，生成基因限制图 序列，检查RNA转录本的二级结构 产生用于执行的核酸探针的目的 用杂交组织化学方法检测和定量脑内的mRNAs 组织。

This project uses molecular and histochemical techniques to examine how the loss of gonadal function (loss of circulating gonadal steroids) affects the expression of growth factors, growth factor receptors, and enzymes which are implicated in learning and memory processes and in age and disease-related cognitive decline. My use of the supercomputing center will be primarily to search and retrieve nucleic acid sequences for nucleic acid database such as GENEBANK, to perform sequence comparisons, generate restriction maps of gene sequences, examine secondary structure of RNA transcripts all for the purpose of generating nucleic acid probes for use in performing hybridization histochemistry to detect and quantify mRNAs in brain tissue.