TRAINING PROGRAM IN DEVELOPMENTAL IMMUNOLOGY

近年来，在对基本工作原理的理解上发生了一场革命。 哺乳动物免疫系统。 这场革命是由进步推动的 在技术方面，特别是在分子遗传学领域， “逆转”遗传学，以及创造性地整合新技术 用更“经典”的方法。 这将是下一个挑战 新一代的免疫学家应用这些最近获得的知识， 更深入地了解人类疾病的过程。 这将需要广泛的教育，不仅在现代技术， 而且在“经典”方法和似乎 目前与磁场相切。 这是本建议的目的 在发育免疫学的培训计划，以提供这样的教育 有扎实科学背景的人。 该培训计划将 利用来自杰斐逊医学院和 福克斯大通癌症中心，分享重叠的利益有关的 发展免疫反应和抵抗传染病。 博士前学生将参加免疫学的核心课程， 最初包括免疫学基础课程， 生物化学和分子生物学，以及选修入门课程 其他学科的课程，如遗传学，细胞生物学， 微生物学. 随后是更高级的课程，包括 病毒学，分子免疫学和免疫遗传学，细胞免疫学， 免疫病理学，免疫寄生虫学和其他选修课。 学生 要求在研究导师的实验室进行三次轮换 对免疫学或传染病感兴趣的学生， 论文指导老师。 学生定期参加 在整个培训过程中进行研讨会，并要求提交他们的 每年两次向论文研究委员会提交研究进展报告。 与 论文研究委员会的咨询和监督 免疫学研究生学习委员会，学生可以调整课程 符合他/她的兴趣或先前的经验。 学生不断 在整个培训过程中进行监测和评估，并必须通过 在他们的课程结束时，以口头形式进行综合考试 一份书面的申请书。 攻读博士学位的课程。学位是开放给学生谁持有 一个学士学位，从认可的机构谁希望进入 生物医学研究，以及已经或将获得 其他专业学位（医学博士，D.O.，D.V.M.，或D.D.S.）并希望 追求独立的学术研究生涯。 接受是基于 平均绩点、GRE成绩、研究经验等标准。字母 推荐信和面试 博士后项目申请人必须持有博士学位或同等学历 博士学位，并接受将取决于过去的研究和 教育经验。 该计划的目标是高度发展 受过培训的、技术胜任的研究科学家， 最终指导免疫学研究。

Recent years have seen a revolution in understanding of the basic workings of the mammalian immune system. This revolution has been driven by advance in technology, particularly in the areas of molecular genetics and "reversed" genetics, as well as by creative integration of new technologies with more "classical" approaches. It will be the challenge of the next generation of Immunologists to apply the knowledge gained by these recent advances towards a more detailed understanding of human disease processes. This will require an extensive education not only in the modern techniques, but also in "classical" approaches and in areas that appear to be tangential to the field at present. It is the purpose of this proposed training program In Developmental Immunology to provide such an education to individuals with solid science backgrounds. This training program will utilize a select group of faculty from Jefferson Medical College and from the Fox Chase Cancer Center that share overlapping interests related to the development of immune responses and resistance to infectious disease. Predoctoral students will take a core curriculum in Immunology which consists initially of courses in the Fundamentals of Immunology, Biochemistry, and Molecular Biology, and a choice of elective introductory courses in other disciplines such as Genetics, Cell Biology, and Microbiology. This is followed by more advanced courses including Virology, Molecular Immunology and Immunogenetics, Cellular Immunology, Immunopathology, Immunoparasitology and other electives. Students are required to do three rotations in the laboratories of research preceptors with interests in Immunology or Infectious Disease before choosing a preceptor and direction for thesis work. Students periodically persent seminars throughout their training and are required to present their research progress to their Thesis Research Committee twice a year. With the consultation of the Thesis Research Committee and the supervisory Immunology Graduate Studies Committee, the student may adapt the curriculum to fit his/her interests or prior experience. Students are constantly monitored and evaluated throughout their training and must pass a comprehensive exam at the end of their course work in the form of an oral defense of a written grant proposal. The program of study leading to a Ph.D. degree is open to students who hold a Bachelor's degree from an accredited institution who wish to enter biomedical research, as well as individuals who already hold or will obtain other professional degrees (M.D., D.O., D.V.M., or D.D.S.) and who wish to pursue an independent academic research career. Acceptance is based on the criteria of grade point average, GRE scores, research experience,. letters of recommendation, and an interview. For the postdoctoral program, applications must hold a Ph.D, or equivalent doctoral degree, and acceptance will depend upon past research and educational experience. The goal of this program is to develop highly trained, technology competent research scientists capable of performing and ultimately directing research in Immunology.