NURSING MEASUREMENT OF LYMPHEDEMATOUS LIMBS

描述：乳腺癌治疗是乳腺癌患者水肿的主要原因。 美国的200万患有乳腺癌的妇女有可能患上 在他们的一生中，水肿的不精确测量是一种 主要阻碍严格研究的风险因素与 水肿的发展和治疗效果。本研究建议， 评价并比较两种最先进的肢体体积测量方法， 40例乳腺癌后水肿妇女的“金标准”测量 治疗主要的具体目标是评估信度，效度， 灵敏度和实用性的两个措施的肢体体积（顺序 圆周肢体测量和红外激光测量， perometer）与作为“黄金标准”测量的水置换相比。一 第二个目的是评估和比较生理参数（组织 氧合和皮肤温度）。这些目标 将通过实验室评估（连续肢体 周长，perometry和水位移）在两个时间点与一个 4-每例受试者在同一天的时间间隔为1小时。两个测量值在 设计不同的时间点来评估和比较 这3种模式用于捕获肢体体积随时间的变化。发现将 指导选择可靠、有效、灵敏和实用的测量方法 轻度至重度水肿的护理评估和转换方案 时间这项工作的顺利完成，将为今后的护理工作奠定基础 研究的目的是：（1）测试有针对性的干预措施的有效性， 预防、控制或解决继发于乳腺癌治疗的水肿， 2）测试干预措施的有效性，以实现其他相关目标 对乳腺癌妇女的生活质量很重要的结果 癌

DESCRIPTION: Breast cancer treatment is the leading cause of lymphedema in the United States. Two million women with breast cancer are at risk to develop lymphedema during their lifetimes. Imprecise measurement of lymphedema is a major deterrent to rigorous research on risk factors associated with the development of lymphedema and treatment efficacy. This study proposes to evaluate and compare two state of the art measures of limb volume compared to a "gold standard" measure in 40 women with lymphedema following breast cancer treatment. The primary specific aim is to assess the reliability, validity, sensitivity, and practicality of two measures of limb volume (sequential circumferential limb measurement and infrared laser measurement with the perometer) compared to water displacement as the "gold standard" measure. A secondary aim is to assess and compare physiological parameters (tissue oxygenation and skin temperature) in affected and non-affected arms. These aims will be accomplished through laboratory assessments (sequential limb circumferences, perometry, and water displacement) at two points in time with a 4-hour interval on the same day for each subject. The two measurements at different points in time are designed to assess and compare the sensitivity of the 3 modalities to capture changes in limb volume over time. Findings will guide the selection of a reliable, valid, sensitive, and practical measurement protocol for nursing assessment of mild to severe lymphedema and changes over time. Successful completion of this work will lay the foundation for a nursing study aimed at 1) testing the effectiveness of targeted interventions to prevent, control, or resolve lymphedema secondary to breast cancer treatment, and 2) testing the effectiveness of interventions to achieve other associated outcomes that are important for the quality of life of women with breast cancer.