CRITICAL ASSESSMENT OF PROTEIN STRUCTURE PREDICTION CASP

要求支持一项社区范围的实验， 评估蛋白质结构预测的最新技术水平， 序列（CASP）。这是该系列的第四个实验。先前 1994年、1996年和1998年进行了试验。21个国家的98个小组 去年，各国共提交了约4000份预测报告， 实验我们的目标是对我们的工作进行深入和客观的评估。 目前的能力，并评估自上次实验以来的进展。 关于即将解决的结构的信息将从 实验社区，并预测这些目标的结构 收集和评估。收集预测的工作将于2000年4月开始， 一直到八月会议将在阿西洛马会议上举行 中心在加州在2000年12月，预测后， 评估。有关整个过程的信息将在一个网站上提供 绝佳的价钱该提案要求为会议的组织和 实验的组成部分。所有数据处理将在 劳伦斯利弗莫尔预测中心，单独资助。

Support is requested for a community wide experiment to critically assess the current state of the art in the prediction of protein structure from sequence (CASP). This is the fourth experiment in the series. Previous experiments were held in 1994, 1996 and 1998. Ninety-eight groups from 21 countries submitted a total of approximately 4000 predictions in the last experiment. The goal is to provide an in-depth and objective assessment of our current abilities, and to assess progress since the last experiment. Information about soon to be solved structures will be solicited from the experimental community, and predictions of the structures of those targets collected and assessed. The collection of predictions will begin in April 2000, and run through August. The meeting will take place at the Asilomar Conference Center in California in December 2000, after the predictions have been assessed. Information about the complete process will be provided at a web site. This proposal requests support for the organizational and meeting components of the experiment. All data processing will be handled at the Lawrence Livermore Prediction center, separately funded.