Developmental Switches in Spermatogenesis

我寻求所需的知识，以改善预防，诊断和治疗男性睾丸病理通过研究什么控制早期精子发育。我的研究将描述细胞信号分子如何为成人生育奠定基础，使用动物研究，细胞培养和临床样本。来自睾丸癌患者的睾丸样本将用于测试可能杀死肿瘤细胞或为精子发生受损的男性提供治疗选择的干预措施。

I seek the knowledge required to improve prevention, diagnosis and therapy for men with testicular pathologies by studying what controls early sperm development. My research will delineate how cellular signalling molecules lay the foundation for adult fertility, using animal studies, cell culture and clinical samples. Testis samples from testicular cancer patients will be used to test interventions that may kill tumour cells or offer a therapeutic option to men with impaired spermatogenesis.