TRAINING PROGRAM IN DEVELOPMENTAL IMMUNOLOGY

近年来，人们对基本工作原理的理解发生了一场革命 哺乳动物的免疫系统。这场革命是由前进推动的。 在技术方面，特别是在分子遗传学和 “逆转”的遗传学，以及创造性地整合新技术 采用更“经典”的方法。这将是下一步的挑战 新一代免疫学家应用这些最近获得的知识 在更详细地理解人类疾病过程方面取得了进展。 这将需要广泛的教育，不仅是现代技术， 但也是在“经典”方法和似乎是 目前与这一领域无关。这就是这项提议的目的 提供这种教育的发育免疫学培训计划 给有扎实科学背景的个人。这项培训计划将 利用杰斐逊医学院和 福克斯·蔡斯癌症中心分享与 发展免疫反应和对传染病的抵抗力。 博士前学生将选修免疫学的核心课程 最初由免疫学基础课程组成， 生物化学、分子生物学和选修课导论 其他学科的课程，如遗传学、细胞生物学和 微生物学。接下来是更高级的课程，包括 病毒学、分子免疫学和免疫遗传学、细胞免疫学、 免疫病理学、免疫寄生虫学和其他选修课。学生们 需要在研究导师的实验室里做三次旋转 对免疫学或传染病感兴趣的人在选择 论文工作的指导者和方向。学生定期出席 在他们的培训期间举办研讨会，并被要求提交其 研究进展每年向他们的论文研究委员会报告两次。使用 论文研究委员会与监事会的协商 免疫学研究生委员会，学生可以调整课程设置 符合他/她的兴趣或以前的经验。学生们不断地 在整个培训过程中受到监控和评估，并必须通过 在课程结束时以口头形式完成的综合考试 为一份书面拨款提案辩护。 攻读博士学位的课程对持有 希望进入的认可机构颁发的学士学位 生物医学研究，以及已经持有或将获得 其他专业学位(M.D.、D.O.、D.V.M.或D.D.S.)以及谁想要 追求独立的学术研究事业。接受是基于 平均成绩、GRE成绩、研究经验等标准。书信 推荐信和面试。 对于博士后项目，申请者必须拥有博士学位或同等学历 博士学位，是否被接受将取决于过去的研究和 教育经验。这项计划的目标是高度发展 训练有素、有技术能力的研究科学家，能够 最终指导免疫学研究。

Recent years have seen a revolution in understanding of the basic workings of the mammalian immune system. This revolution has been driven by advance in technology, particularly in the areas of molecular genetics and "reversed" genetics, as well as by creative integration of new technologies with more "classical" approaches. It will be the challenge of the next generation of Immunologists to apply the knowledge gained by these recent advances towards a more detailed understanding of human disease processes. This will require an extensive education not only in the modern techniques, but also in "classical" approaches and in areas that appear to be tangential to the field at present. It is the purpose of this proposed training program In Developmental Immunology to provide such an education to individuals with solid science backgrounds. This training program will utilize a select group of faculty from Jefferson Medical College and from the Fox Chase Cancer Center that share overlapping interests related to the development of immune responses and resistance to infectious disease. Predoctoral students will take a core curriculum in Immunology which consists initially of courses in the Fundamentals of Immunology, Biochemistry, and Molecular Biology, and a choice of elective introductory courses in other disciplines such as Genetics, Cell Biology, and Microbiology. This is followed by more advanced courses including Virology, Molecular Immunology and Immunogenetics, Cellular Immunology, Immunopathology, Immunoparasitology and other electives. Students are required to do three rotations in the laboratories of research preceptors with interests in Immunology or Infectious Disease before choosing a preceptor and direction for thesis work. Students periodically persent seminars throughout their training and are required to present their research progress to their Thesis Research Committee twice a year. With the consultation of the Thesis Research Committee and the supervisory Immunology Graduate Studies Committee, the student may adapt the curriculum to fit his/her interests or prior experience. Students are constantly monitored and evaluated throughout their training and must pass a comprehensive exam at the end of their course work in the form of an oral defense of a written grant proposal. The program of study leading to a Ph.D. degree is open to students who hold a Bachelor's degree from an accredited institution who wish to enter biomedical research, as well as individuals who already hold or will obtain other professional degrees (M.D., D.O., D.V.M., or D.D.S.) and who wish to pursue an independent academic research career. Acceptance is based on the criteria of grade point average, GRE scores, research experience,. letters of recommendation, and an interview. For the postdoctoral program, applications must hold a Ph.D, or equivalent doctoral degree, and acceptance will depend upon past research and educational experience. The goal of this program is to develop highly trained, technology competent research scientists capable of performing and ultimately directing research in Immunology.