CELL ADHESION AND EFFECTS ON CELL BEHAVIOR

描述（申请人描述）：这是一份关于细胞，分子和结构生物学领域“细胞粘附及其对细胞行为的影响”的博士后培训的更新申请。这17名导师是该研究所四个科学项目的成员。这些课程是细胞外基质和细胞粘附，发育神经生物学，糖生物学和干细胞生物学。培训计划的扩大是该研究所在数量和质量上的增长以及在选择和培训从事生物医学研究的博士后方面越来越成功的结果。受训者的任期为1-2年，期满后可申请其他资助来源的博士后培养，也可申请独立职位和资助。伯纳姆研究所配备了先进的研究技术，并拥有通过胚胎干细胞同源重组进行基因靶向的设备，用于转基因小鼠生产和其他动物实验，用于DNA合成和自动DNA测序，用于电子和共聚焦显微镜，用于晶体学，核磁共振和计算。伯纳姆研究所目前有120名博士后正在接受为期2-5年的培训。一系列正式和非正式的研讨会补充了实验室培训。关于时间管理、公开演讲、拨款写作、监督和科学伦理等主题的辅助科学研讨会补充了研究培训，并为学员独立的职业生涯做好准备。

DESCRIPTION (Applicant's Description): This is a renewal application for 7 positions for postdoctoral training in cell-, molecular-, and structural biology in the area of "cell adhesion and effects on cell behavior." The 17 preceptors are members of four scientific programs at the Institute. These programs are Extracellular Matrix and Cell Adhesion, Developmental Neurobiology, Glycobiology, and Stem Cell Biology. The expansion of the Training Program is a consequence of the quantitative and qualitative growth of the Institute and the increasing success in selecting and training postdoctoral fellows for a career in biomedical research. The trainees are selected for 1-2 years of tenure, after which they should either be qualified to apply for further postdoctoral training from other funding sources or to apply for independent positions and funding. The Burnham Institute is very well equipped for state-of-the-art research techniques, and has facilities for gene targeting through homologous recombination in embryonic stem cells, for transgenic mouse production and other animal experiments, for DNA synthesis and automatic DNA sequencing, for electron- and confocal microscopy, for crystallography, NMR, and computing. The Burnham Institute currently has 120 post- doctoral fellows in training for periods of 2-5 years. Series of formal and informal seminars complement the laboratory training. Parascientific seminars on topics such as time management, public speaking, grant writing, supervising, and ethical aspects of science complement the research training and prepare the trainees for independent careers.