SYMPATHETIC NERVOUS SYSTEM EFFECTS ON CELL ADHESION

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Determine if sympathetic nervous system activation will result in differential effects on cellular adhesion molecules, result in a significant increase in leukocyte transendothelial migration and whether hypertensives will show different patterns of cellular adhesion molecules following sympathetic nervous system activation with a greater decrease in l-selectin expression and with greater rate of leukocyte transendothelial migration.