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ACTG300 COMBINED ZIDOVUDINE LAMIVUDINE VS BETTER OF DDI MONOTHERAPY V

ACTG300 COMBINED ZIDOVUDINE LAMIVUDINE VS BETTER OF DDI MONOTHERAPY V
ACTG300 联合齐多夫定 拉米夫定 VS 更好的 DDI 单疗法 V
批准号：
6264907
负责人：
MARGARET A KELLER
金额：
$0.1万
依托单位：
LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6264907
关键词：
2'3' dideoxyinosine AIDS therapy HIV infections clinical research combination chemotherapy communicable disease control drug adverse effect drug screening /evaluation female human pregnant subject human subject human therapy evaluation lamivudine vertical transmission zidovudine

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中文摘要
翻译
目的：比较3TC和ZDV治疗HIV感染孕妇及其婴儿的安全性、耐受性和有效性。看看服用这些药物组合是否会进一步降低婴儿感染艾滋病毒的风险。
英文摘要
To determine the safety, tolerance and effectiveness of treatment with 3TC and ZDV, versus ddI versus ddI and ZDV when given to HIV-infected pregnant women and their babies. To see if taking these combinations of medications will further reduce the risk of HIV infections to the baby.
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会议论文
INTENSIVE PHARMACOKINETIC STUDIES OF ANTIRETROVIRAL DRUG COMBINATIONS HIV
INTENSIVE PHARMACOKINETIC STUDIES OF ANTIRETROVIRAL DRUG COMBINATIONS
Two-Dimensional 3 Tesla MRS of the Brain in HIV- Infected Youth
PHARMACOKINETIC PROPERTIES OF ANTIRETROVIRAL THERAPY DURING PREGNANCY
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