LOSIGAMONE AS MONOTHERAPY IN TREATMENT OF COMPLEX PARTIAL SEIZURES

与NIH癫痫分部和其他12个临床中心合作的全面癫痫计划将提供90名已完成患者的数据。综合癫痫计划将确定该计划目前使用的计算机化癫痫患者日志跟踪的候选人。这项为期21个月的试验的潜在候选人的进一步确定预计将来自3名内科医生、1名咨询内科医生和2名药剂师，其中1名负责具体的患者任务。两名护士协调员和一名数据录入协调员将担任后备，完成研究团队。GCRC将进一步管理病人的随访和抽血服务，并提供住院和门诊服务。需要在医院过夜进行滴定，以满足患者的最佳剂量需求。在七个月的注册期间，需要两次过夜访问。

The comprehensive epilepsy program in conjunction with the Epilepsy Branch of NIH and 12 other clinical centers will provide data on 90 completed patients. The Comprehensive Epilepsy program will identify candidates tracked by the computerized epilepsy patient log currently utilized by the program. Further identification of potential candidates for this 21 month trial is expected to come from 3 physicians, 1 consulting physician, and 2 pharmacists with one performing specific patient tasks. Two nurse coordinators with on acting as backup and a data entry coordinator will complete the research team. Further management of patient follow-up and phlebotomy services will be performed by the GCRC with provisions for inpatient and outpatient visits. Overnight hospitalization is required for titration to meet the patient's optimal dosing needs. An overnight visit is required twice throughout the seven month enrollment period.