CORE--CLINICAL

临床核心旨在为以下方面提供成本效益高的支持 所有项目的临床研究。研究护理和技术 支持招募受试者，维护共享 设备，用于安排共享的人体生理学实验室，以及 为准备和个人研究的性能将更多 由核心提供的效率高于个人提供的效率。 项目具有临床研究专业知识的研究者， 去甲肾上腺素、生化、全身和局部去甲肾上腺素溢出 2010年1月1日至2011年12月31日期间， 个人研究表现，以及数据分析和 处理，提高能力的所有项目顺利完成 这些研究。氚化去甲肾上腺素，一种昂贵的供应品， 为节省成本，将大量购买和制备具有规定半衰期的化学品。 最后，来自几个项目的调查人员的参与， 临床核心活动将增加项目之间的沟通， 增加了本计划项目的综合性。

The Clinical Core is designed to provide cost effective support for the clinical studies in all projects. Research nursing and technical support for the recruitment of subjects, for the maintenance of shared equipment, for the scheduling of shared Human Physiology laboratories, and for preparation for and performance of individual studies will be more efficiently provided by the Core than would be possible for the individual projects. Investigators with expertise in clinical studies, norepinephrine, biochemistry, and systemic and local norepinephrine spill over will provide for maintenance of complex equipment, backup for individual study performance, and a shared resource for data analysis and handling, enhancing the ability of all projects to successfully complete these studies. Tritiated norepinephrine, a costly supply item with a defined half-life, will be purchased and prepared in bulk for cost saving. Finally, the involvement of investigators from several projects in Clinical Core activities will increase communication between projects, adding to the integrative nature of this Program Project.