EPIDEMIOLOGY STUDY OF THE LATE REPRODUCTIVE YEARS

这是一项对荷尔蒙和症状的纵向研究，以表征 脱氢表雄酮、卵泡刺激素、黄体生成素和雌二醇的波动和变化率及检测 假设1)症状与这些荷尔蒙的变化有关； 2)DHEAS可能对心理症状有直接影响；3) 心理症状与以下情况无关且发生在 血管舒缩症状；以及4)症状和激素的任何差异 非裔美国人和高加索女性之间的差异可以忽略不计 控制已知用于区分这些组的背景变量。 以人口为基础的样本有400名女性(200名非裔美国人，200名 高加索人)，注册时年龄为35-47岁，每隔9个月进行一次跟踪 已经5年了。这项研究将提供目前重要的信息 了解症状和荷尔蒙之间的关系。

This is a longitudinal study of hormones and symptoms to characterize the fluctuations and rates of change of DHEAS, FSH, LH and estradiol and test hypotheses that 1) symptoms are associated with changes in these hormones; 2) DHEAS may have a direct effect on psychological symptoms; 3) psychological symptoms are not correlated with and occur prior to vasomotor symptoms; and 4) any differences in symptoms and hormones between African-American and Caucasian women is negligible after controlling for background variables known to differentiate these groups. The population-based sample has 400 women (200 African-American, 200 Caucasian), ages 35-47 at enrollment and is followed at 9-month intervals for 5 years. The study will provide important information that is now know about relationships between symptoms and hormones.