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CONCURRENT RADIATION AND GERCITABINE FOR UNRESECTABLE HEAD AND NECK TUMORS

CONCURRENT RADIATION AND GERCITABINE FOR UNRESECTABLE HEAD AND NECK TUMORS
同步放疗和吉西他滨治疗不可切除的头颈部肿瘤
批准号：
6244598
负责人：
Avraham Eisbruch
金额：
$2.22万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-02-20 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6244598
关键词：
antineoplastics blood chemistry clinical research clinical trial phase I combination cancer therapy drug metabolism drug screening /evaluation head /neck neoplasm human subject human therapy evaluation neoplasm /cancer chemotherapy neoplasm /cancer radiation therapy

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中文摘要
翻译
这是我研究的一个阶段，寻求最大耐受量 吉西他滨与标准疗程的放射治疗同步进行 不能切除的头颈部肿瘤患者。血浆水平和 吉西他滨的肿瘤掺入以及肿瘤核苷酸库 为了更好地了解 吉西他滨增强放射抗肿瘤作用的机制 活体内活动。
英文摘要
This is a phase I study seeking the maximally tolerated dose of gemcitabine delivered concurrent with a standard course of radiation for patients with unresectable head and neck tumors. Plasma levels and tumor incorporation of gemcitabine, as well as tumor nucleotide pools will be measured in order to gain a better understanding of the mechanisms by which gemcitabine may enhance radiation antitumoral activity in vivo.
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INDIVIDUALIZING IMRT TREATMENT IN BRAIN AND HEAD/NECK CA
CONCURRENT RADIATION AND GEMCITABINE FOR UNRESECTABLE HEAD AND NECK TUMORS
QUALITY OF LIFE IN HEAD AND NECK CANCER
QUALITY OF LIFE IN HEAD AND NECK CANCER
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